The detection of drugs by histochemical procedures

  • M. Morley
Chapter

Abstract

Many methods of analysis are available to the toxicologist for determining the type and amount of drug within human tissues, but few have the potential of histochemistry for enabling the precise site of action of a drug to be defined. Histochemistry is essentially the examination of the chemical as opposed to the morphological structure of tissue preparations. Nondiffusible coloured or fluorescent reaction products which can be visualised under the microscope indicate the cellular localisation of the endogenous or exogenous substances under investigation.

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Further Reading Affinity Chromatography

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Fluorescence

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Histochemistry

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Immunoenzyme techniques

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© The contributors 1984

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  • M. Morley

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