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Antibiotics affecting microbial cell walls: Progress after 112 years

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Chemotherapeutic Strategy
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Abstract

Although the beta-lactam antibiotics are by the far the most important therapeutic agents that act by inhibiting bacterial cell-wall peptidoglycan synthesis, several other totally unrelated antibiotics act at earlier stages of this essential pathway (Selwyn, 1980a). The clinically significant members of this miscellaneous group of drugs are bacitracin, vancomycin, cycloserine and phosphomycin. Others of less importance include novobiocin and ristocetin. The current position in relation to each can be briefly reviewed.

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Selwyn, S. (1983). Antibiotics affecting microbial cell walls: Progress after 112 years. In: Edwards, D.I., Hiscock, D.R. (eds) Chemotherapeutic Strategy. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-06540-0_4

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  • DOI: https://doi.org/10.1007/978-1-349-06540-0_4

  • Publisher Name: Palgrave Macmillan, London

  • Print ISBN: 978-1-349-06542-4

  • Online ISBN: 978-1-349-06540-0

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