Discussion

  • Earl Usdin
  • Norman Weiner
  • Moussa B. H. Youdim

Abstract

The discussion after Dr. Tipton’s presentation centered on his observation that although acetaldehyde as well as biogenic aldehydes were all substrates for the aldehyde dehydrogenases of brain and liver, little competition between added acetaldehyde and the metabolism of biogenic amines could be demonstrated in slices of liver. Questions were posed by Drs. H. Weiner and Tabakoff regarding various forms of the dehydrogenase- and aldehyde-induced shifts in the redox state of the slices: Dr. Tipton proposed that added acetaldehyde produces little shift in redox due to metabolism by alcohol as well as aldehyde dehydrogenase.

Keywords

Aldehyde Adduct Disulfide Tral Monoamine 

Copyright information

© The Contributors 1981

Authors and Affiliations

  • Earl Usdin
    • 1
  • Norman Weiner
    • 2
  • Moussa B. H. Youdim
    • 3
  1. 1.National Institute of Mental HealthUSA
  2. 2.University of ColoradoUSA
  3. 3.Technion Faculty of MedicineUSA

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