Possible Physiological Roles of the Enkephalins and Endorphins

  • H. W. Kosterlitz

Abstract

In the evaluation of the possible physiological roles of new neurotransmitters or neuromodulators, it is necessary to understand the mechanisms underlying their biosynthesis, release and metabolism, and interactions with their receptors. There is now a considerable amount of information on these aspects with regard to the endogenous opioid peptides, which has recently been reviewed from the basic and clinical points of view (Kosterlitz & McKnight, 1980, 1981). For this reason, it is intended to deal in this paper mainly with those concepts that are important for an understanding of the principles governing the possible physiological functions of the enkephalins and endorphins.

Keywords

Dopamine Schizophrenia Respiration Testosterone Alkaloid 

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Copyright information

© The contributors 1980

Authors and Affiliations

  • H. W. Kosterlitz
    • 1
  1. 1.Unit for Research on Addictive DrugsUniversity of AberdeenAberdeenScotland, UK

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