Catecholaminergic Enzymes in Parkinson’s Disease and Related Extrapyramidal Diseases
The observation on the decrease in dopamine(Ehringer and Hornykiewicz, 1960) and in aromatic L-amino acid decarboxylase activity with DOPA as a substrate (DOPA decarboxylase activity) (Lloyd and Hornykiewicz, 1970) in the dopaminergic regions of the parkinsonian brain indicated the disturbance in dopamine biosynthesis.
KeywordsHPLC Dopamine Tyrosine Pneumonia Noradrenalin
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