The summing up

  • Arnold Burgen
Part of the Biological Council book series


Receptors in the sense used in this symposium fall into two classes, namely those on the outer surface of the membrane whose message must be transmitted to the cell interior and those already in the interior. The first of these classes is embedded in a membrane and is constrained to act in two dimensions, and it is all too tempting to regard the lipid phase of the membrane as a passive supporting matrix, yet the effects on phospholipid turnover described in this symposium point not only to a more dynamic role for the lipid, but perhaps even to a metabolic imperative occurring in the relatively anhydrous environment of the lipid leaflet. Yet there are events at the motor end-plate and in the sino-auricular node which seem free of this requirement and are concerned with coupling between receptor and ionophoric channels.

Copyright information

© Institute of Biology Endowment Trust Fund 1981

Authors and Affiliations

  • Arnold Burgen
    • 1
  1. 1.National Institute for Medical ResearchMill Hill, LondonUK

Personalised recommendations