Identification and separation of mouse and human components of heterotransplanted human tumours
It has been demonstrated that, with the exception of foetal tissues (Povlsen et al., 1974) normal cells will not grow when injected into immunosuppressed animals (Stanbridge et al., 1975). It might thus be expected that heterotransplantation of human tumours into immunosuppressed mice might result in replacement of the stromal elements by mouse stroma.
KeywordsImmunosuppressed Mouse Heterotransplanted Tumour Polystyrene Tissue Culture Dish Mouse Mammary Carcinoma Cell Line HT29R Cell
Unable to display preview. Download preview PDF.
- Stanbridge, E. J., Boulger, L. R., Franks, C. R., Garrett, J. A., Reeson, D. E., Bishop, D. and Perkins, F. T. (1975). Optimal conditions for the growth of malignant human and animal cell populations in immunosuppressed mice. Cancer Res, 35, 2203–12Google Scholar
- Van Kleist, S., Chany, E., Bartin, P., King, M. and Fogh, J. (1975). Immunohistology of the antigenic pattern of a continuous cell line from a human colon tumour. J. natn. Cancer Inst, 55, 555–60Google Scholar