Drug selectivity in the suppression of the immune response

  • E. Mihich
Part of the Biological Council Co-ordinating Committee for Symposia on Drug Action book series (BCSDA)


Chemotherapy is a relatively effective treatment for certain types of neoplastic diseases. In fact, by using drugs alone or in combination, good quality life can be prolonged and, in some cases, complete remission can be obtained with no evidence of the disease being found five years or more after diagnosis. These therapeutic results are obtained in patients with certain types of choriocarcinoma, Wilm’s tumour, Burkitt’s lymphoma, acute lymphocytic leukaemia and certain tumours of the skin. In the near future, chemotherapeutic treatments in conjunction with surgery may provide additional examples of therapeutic efficacy, as in the case of osteogenic sarcoma of the limb and of pre-menopausal breast tumours.


Spleen Cell Selective Effect Immunise Mouse Dihydrofolate Reductase Drug Selectivity 
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Copyright information

© Institute of Biology Endowment Trust Fund 1979

Authors and Affiliations

  • E. Mihich
    • 1
  1. 1.Department of Experimental Therapeutics and Grace Cancer Drug CenterRoswell Park Memorial Institute, New York State Department of HealthBuffaloUSA

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