Abstract
The recent emergence of a physiology of analgesia and behavior is based on the demonstration of a morphine receptor (Goldstein et al., 1971) followed by the isolation and characterization of peptides with opioid or behavioral activity, that is, enkephalins (Hughes et al., 1975) and β-endorphin (Li and Chung, 1976). The precursor relationship of β-lipotropin (β-LPH) to the opioid peptides was then realized. Since then, other congeners of enkephalin and endorphin have been reported in tissues.
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Udenfriend, S., Rubinstein, M., Stein, S. (1979). A re-evaluation of the opioid peptides present in the central nervous system utilizing microfluorometry. In: Usdin, E., Bunney, W.E., Kline, N.S. (eds) Endorphins in Mental Health Research. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-04015-5_11
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DOI: https://doi.org/10.1007/978-1-349-04015-5_11
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