Experimental Membrane Oxygenators with Convective Mixing for Gas Transfer Augmentation
Principle of operation, design and oxygenation performance of three membrane oxygenators employing convective mixing for enhanced gas transfer are described. Two oxygenators are of curved rectangular channel geometry, one with vortex formation induced by pressure driven flow and the second with vortices generated by torsional oscillation of the channel. The third oxygenator is of the capillary membrane type incorporating a chamber which functions as a mixing stage and a blood pump. The efficiencies of the units are compared with existing membrane oxygenators and design optimisation of the most promising system is presented.
Unable to display preview. Download preview PDF.
- Bellhouse, B. J., Bellhouse, F. H., Curl, C. M., MacMillan, T. I., Gunning, A. J., Spratt, E. H., MacMurray, S. B. and Nelems, J. M. (1973). A high efficiency membrane oxygenator and pulsatile pumping system, and its application to animal trials. Trans. Amer. Soc. Artif. Int. Organs, 19, 72.CrossRefGoogle Scholar
- Gilroy, K. (1976). Secondary flow augmented mass transfer in annular membrane oxygenators. Ph.D. Thesis, University of Strathclyde, Glasgow.Google Scholar
- Hill, J. D., Iatridis, A., O’Keefe, R. and Kitrilakis, S. (1974). Technique for achieving high gas exchange rates in membrane oxygenation. Trans. Amer, Soc. Artif. Int. Organs, 20, 249.Google Scholar
- Mockros, L. F. and Weissman, M. H. (1971). The artificial lung, in J. H. U. Brown,J. E. Jacobs, and L. Stark, (Eds.), Biomedical Engineering, Davis Company,California, p. 325. Reid, W. H. (1958). On the stability of viscous flow in a curved channel. Proc. Roy. Soc. (London), A 244, 186.Google Scholar
- Ton, H. Y. (1975). Design of a tubular membrane oxygenator with integral pumping. M.Sc. Thesis, University of Strathclyde, Glasgow.Google Scholar