Factors Inherent in the Host Affecting Establishment and Course of Disease
Any infection course is a result of interactions between pathogen and host resulting in different mechanisms of their effects on the host and host population. The inherent factors may be classified according to the manner in which they affect infections. Morphological and physiological properties of the host may directly influence (1) establishment of infection and (2) course of infection. And they may indirectly affect infection by providing conditions for interaction between pathogen and other microorganisms, e.g. by providing exudates that affect the microflora of the environment, particularly the soil microflora (rhizosphere effect); or by providing conditions for establishment of latent infection by other micro-organisms which then may affect the interactions between pathogen and host. A complicated system of such different factors operates in any host-pathogen interaction.
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