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Nephro-Urological Involvement

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Sjögren’s Syndrome

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Abstract

One of the parenchymal organs that can be affected in patients with Sjögren’s ­syndrome (SS) is the kidney [1]. Kidneys in primary SS (pSS) can be a target of the immune system either by activated lymphocytes that infiltrate the renal interstitium resulting in interstitial nephritis (IN) or by an immune complex mediated process appearing as glomerulonephritis (GN). Furthermore, epidemiologic and immunologic data suggest an association between SS and painful bladder syndrome/interstitial cystitis (PBS/IC), a chronic pelvic pain syndrome that produces lower urinary symptoms such as discomfort related to bladder, nocturia, frequency, and urge to void [1].

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Authors and Affiliations

  1. Department of Pathophysiology, School of Medicine, University of Athens, Athens, Greece

    Andreas V. Goules & Haralampos M. Moutsopoulos

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  1. Andreas V. Goules
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  2. Haralampos M. Moutsopoulos
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Editors and Affiliations

  1. Barcelona, Surgey, Hospital Clinic, Calle Villarroel, 170, Barcelona, 08036, Spain

    Manuel Ramos-Casals

  2. Massachusetts General Hospital, Boston, 02114, Massachusetts, USA

    John H. Stone

  3. National University of Athens, Athens, Greece

    Haralampos M. Moutsopoulos

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Goules, A.V., Moutsopoulos, H.M. (2011). Nephro-Urological Involvement. In: Ramos-Casals, M., Stone, J., Moutsopoulos, H. (eds) Sjögren’s Syndrome. Springer, London. https://doi.org/10.1007/978-0-85729-947-5_19

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