Abstract
The use of 3-dimensional (3D) imaging to enhance radiation delivery for gynecologic malignancies has increased dramatically in the past decade. Advances in technology have permitted a rapid evolution in the fields of intensity-modulated radiation therapy (IMRT), image-guided radiation therapy (IGRT), and 3D image-planned brachytherapy (3DBT). In cervical and endometrial cancer, significant progress has been made in the implementation of postoperative IMRT. The use of IMRT and IGRT in the setting of locally advanced gynecologic cancer remains controversial due to issues surrounding organ and tumor changes during the course of treatment. Advantages of and controversies over the use of IMRT, IGRT, and 3DBT will be discussed in detail. Specifically, the role of proper target delineation and the importance of accurate contouring, the problem of organ motion and tumor tracking, and an overview of clinical outcomes will be presented. The use of these new technologies remains in its early development, with the potential for substantial progress in the future.
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Viswanathan, A.N., Lindegaard, J.C. (2014). Do Intensity-Modulated Radiation, Image-Guided Radiation, and 3D Brachytherapy Significantly Advance Radiotherapeutic Management of Gynecologic Cancers?. In: Ledermann, J., Creutzberg, C., Quinn, M. (eds) Controversies in the Management of Gynecological Cancers. Springer, London. https://doi.org/10.1007/978-0-85729-910-9_22
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