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Stereotactic Body Radiotherapy in Head and Neck Cancer

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Stereotactic Body Radiotherapy

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Abstract

There is limited data regarding stereotactic radiotherapy (SRT) or stereotactic body radiotherapy (SBRT) for primary head and neck cancers, although it is feasible using SRT for primary HNC and its potential benefit in LC and organ preservation. The dose conformality by using SBRT and reduced CTV to PTV margins do seem to have a substantial effect on the dose received by the swallowing muscles and parotid glands as opposed to those treated with an IMRT or 3DCRT boost. Hypofractionated SRT may have the potential for curative or palliative treatment and could have a shorter duration of treatment, and a highly conformal dose distribution. However, severe late adverse reactions are anticipated with re-irradiation than with initial RT, partly because of the large doses per fraction used in most series. Compared with stereotactic radiosurgery using single fraction of high-dose irradiation, fractionated stereotactic radiotherapy may be superior in terms of tumor control and protection of normal tissues and organs surrounding the target.

This chapter discusses the role of SBRT in head and neck cancers.

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Acknowledgements

The authors appreciate the contributions in some parts of this chapter by Maarten Paulides, PhD, Gerda M. van de Velde-Verduijn, MD, Noëlle C. van der Voort van Zyp, MD, PhD.

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Authors and Affiliations

  1. Department of Radiation Oncology, Erasmus MC – Daniel den Hoed Cancer Center, Rotterdam, The Netherlands

    David N. Teguh MD, PhD, Peter C. Levendag MD, PhD & Abrahim Al-Mamgani MD, PhD

  2. Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

    Anand Mahadevan MD, FRCS, FRCR

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  1. David N. Teguh MD, PhD
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  2. Peter C. Levendag MD, PhD
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  3. Abrahim Al-Mamgani MD, PhD
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Correspondence to David N. Teguh MD, PhD .

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Editors and Affiliations

  1. Guy's Hospital, London, United Kingdom

    Andrew Gaya

  2. Dept. Radiation Oncology, Harvard Medical School Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

    Anand Mahadevan

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Teguh, D.N., Levendag, P.C., Al-Mamgani, A., Mahadevan, A. (2015). Stereotactic Body Radiotherapy in Head and Neck Cancer. In: Gaya, A., Mahadevan, A. (eds) Stereotactic Body Radiotherapy. Springer, London. https://doi.org/10.1007/978-0-85729-597-2_14

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