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Clinical Facial Composite Tissue Allotransplantation: A Review of the Global Experience and Future Implications

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The Know-How of Face Transplantation

Abstract

Since 2005, 11 facial composite tissue allotransplantations (CTA) have been performed in 8 different centers in 6 countries. Five teams have reported their work and outcomes in separate publications. We review in detail the first four global experiences and compare indications, donor/recipient matching criteria, CTA graft anatomy, immunosuppressive protocols, and postoperative course. A thorough review of the eight publications by five transplantation groups was conducted. Additional information gathered from official press releases were also included for review. Some details of the remaining transplants are also discussed to facilitate evaluation of indications, matching criteria and future directions for facial CTA.

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Abbreviations

CMV:

Cytomegalovirus

CTA:

Composite Tissue Allotransplantation

EBV:

Epstein–Barr Virus

EMG:

Electromyelography

GVHD:

Graft vs. Host disease

NCS:

Nerve Conduction Studies

PSSD:

Pressure-Specified Sensory Device

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Correspondence to Helen G. Hui-Chou .

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Hui-Chou, H.G., Rodriguez, E.D. (2011). Clinical Facial Composite Tissue Allotransplantation: A Review of the Global Experience and Future Implications. In: Siemionow, M. (eds) The Know-How of Face Transplantation. Springer, London. https://doi.org/10.1007/978-0-85729-253-7_31

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  • DOI: https://doi.org/10.1007/978-0-85729-253-7_31

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