Abstract
Infectious complications are a serious cause of morbidity and mortality in cancer patients, especially those with underlying hematologic malignancies. Several large studies have estimated that 70–75% of deaths in patients with acute leukemia are caused by infection, with or without hemorrhage [1–3]. Fewer data exist on infectious mortality in patients with solid organ tumors; however, approximately 50% of these patients are estimated to have an infection as either the primary or an associated cause of death [4,5]. Because patients with underlying malignancies are a heterogeneous group, an epidemiologic review of infections in these patients must take into account the diversity of the patient population. The nature of the underlying malignancy, the immunodeficiencies associated with it, and the treatments directed against it are all important determinants of infection.
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References
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Zembower, T. (1998). Epidemiology of infectious complications in cancer patients. In: Noskin, G.A. (eds) Management of Infectious Complications in Cancer Patients. Cancer Treatment and Research. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38152-7_2
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