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Stiffness of Wall Material in Human Hypertension

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Biology of the Arterial Wall

Part of the book series: Basic Science for the Cardiologist ((BASC,volume 1))

Abstract

Damage of the large arteries is strongly associated with cardiovascular accidents, mainly in the cerebral, the coronary and the renal circulation [1,2]. Because such accidents are observed both in normotensive and hypertensive populations, it has been suggested that a common trigger factor, atherosclerosis, plays a major contributive role in the mechanism of the vascular alterations. However, independently of atherosclerosis, hypertensive vessels are thicker and stiffer than those of corresponding normotensive controls [2–4]. Thus the question is raised to know whether the specific alterations of hypertensive vessels play a role in cardiovascular morbidity and mortality.

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Author information

Authors and Affiliations

  1. Department of Internal medecine and INSERM U337, Broussais Hospital, Paris, France

    Michel E. Safar

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  1. Michel E. Safar
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Editor information

Editors and Affiliations

  1. Lariboisiére hospital, INSERM U141, Paris, France

    Bernard I. Levy  & Alain Tedgui  & 

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© 1999 Kluwer Academic Publishers

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Safar, M.E. (1999). Stiffness of Wall Material in Human Hypertension. In: Levy, B.I., Tedgui, A. (eds) Biology of the Arterial Wall. Basic Science for the Cardiologist, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-0-585-38146-6_11

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  • DOI: https://doi.org/10.1007/978-0-585-38146-6_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-7923-8458-8

  • Online ISBN: 978-0-585-38146-6

  • eBook Packages: Springer Book Archive

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