Anticoagulant Monitoring

  • James M. Wilson
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 193)


Inhibition of normal hemostatic mechanisms is the cornerstone of medical therapy for many cardiovascular diseases. Inhibition of thrombus growth and development is the goal of antithrombotic therapy, yet it results in an increased risk of spontaneous hemorrhage, which may result in substantial morbidity and even death. Therefore, if antithrombotic therapy is to be of value, a delicate equilibrium must be maintained between prevention of pathologic thrombosis and an excess risk of life-threatening hemorrhage.


International Normalize Ratio Prothrombin Time Tissue Factor Partial Thromboplastin Time Thrombin Generation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  • James M. Wilson

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