Abstract
Rising in incidence (2008 US incidence 66,120 and mortality 19,160); median age 60–65 years. Causative conditions: Immunodeficiency – congenital (SCID, ataxia telangiectasia), acquired (HIV, organ transplant), autoimmune (Sjogren’s, Hashimoto’s disease, rheumatoid arthritis, systemic lupus erythematosus). Environmental – chemicals (pesticides and solvents). Viral – EBV (Burkitt’s lymphoma and NK/T cell), HTLV-1 (human lymphotrophic virus, type I; adult T-cell leukemia in southern Japan and Caribbean, spread by breastfeeding, sex and blood products), HHV-8 (Kaposi’s sarcoma), HCV (extranodal B-cell NHL). Bacterial – Helicobacter pylori (MALT). Radiation – weak association. Chemo – alkylating agents.
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Chung, H.T., Shiao, S.L., Schechter, N.R. (2010). Non-Hodgkin’s Lymphoma. In: Hansen, E., Roach, M. (eds) Handbook of Evidence-Based Radiation Oncology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-92988-0_36
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