Abstract
Colorectal cancer (CRC) is the third most common cause of malignancy in both men and women. The incidence rate has decreased over the last two decades partially due to an increase in screening. The American Cancer Society estimates that there are approximately 149,000 new cases of CRC per year and approximately 50,000 patients per year die from this disease in the USA, representing 10% of new cases and 8% of all cancer deaths. Approximately 70–80% of patients are treated with curative intent, mostly by surgery. Chemotherapy alone, or in combination with radiation (for rectal cancer), is given before or after surgery to most patients whose tumor has penetrated the bowel wall or spread to lymph nodes. The overall survival at 1 and 5 years is 82 and 64%, respectively. The 5-year survival is 90% for localized stage, 68% when there is regional spread, and 10% when there are distant metastases.
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Delbeke, D., Walker, R.C. (2010). Colorectal Cancer. In: Delbeke, D., Israel, O. (eds) Hybrid PET/CT and SPECT/CT Imaging. Springer, New York, NY. https://doi.org/10.1007/978-0-387-92820-3_7
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DOI: https://doi.org/10.1007/978-0-387-92820-3_7
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