Skip to main content
  • 1895 Accesses

A 62-year-old man presented with cellulitis. He was found to have pancytopenia with 0% monocytes in the peripheral blood. Physical examination revealed splenomegaly, but no hepatomegaly or lymphadenopathy. The peripheral blood smear showed a few atypical lymphoid cells (Fig. 34.1). A bone marrow aspirate was obtained after two dry taps (Fig. 34.2). The core biopsy revealed patchy distribution of lymphoid aggregates (Fig. 34.3).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 299.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Foucar K, Falini B, Catovsky D, et al. Hairy cell leukemia. In Swerdlow SH, Campo E, Harris NL, et al. eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th ed., Lyon, France, IARC Press, 2008, 188–190.

    Google Scholar 

  2. Pettitt AR, Zusel M, Cawley JC. Hairy cell leukemia: Biology and management. Br J Haematol 1999;106:2–8.

    Article  CAS  PubMed  Google Scholar 

  3. Went PT, Zimpler A, Pehrs AC, et al. High specificity of combined TRAP and DBA-44 expression for hairy cell leukemia. Am J Surg Pathol 2005;29:474–478.

    Article  PubMed  Google Scholar 

  4. Filini B, Tiacci E, Liso A, et al. Simple diagnostic assay for hairy cell leukaemia by immunocytochemical detection of annexin A1 (ANXAI). Lancet 2004;363:1869–1870

    Article  Google Scholar 

  5. Del Giudice I, Matutes E, Morilla R, et al. The diagnostic value of CD123 in B-cell disorders with hairy cell or villous lymphocytes. Haematologica 2004;89:303–308.

    PubMed  Google Scholar 

  6. Cessna MH, Hartung L, Tripp S, et al. Hairy cell leukemia variant: fact or fiction. Am J Clin Pathol 2005;123:132–138.

    Article  PubMed  Google Scholar 

  7. Piris M, Foucar K, Mollejo M, et al. Splenic B-cell lymphoma/leukemia, unclassifiable. In Swerdlow SH, Campo E, Harris NL, et al. eds., WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th ed., Lyon, France, IARC Press, 2008, 191–193.

    Google Scholar 

  8. Traverse-Giehen A, Baseggio L, Callet-Bauchu E, et al. Splenic red pulp lymphoma with numerous basophilic villous lymphocytes: A distinct clinicopathologic and molecular entity? Blood 2008;111:2253–2260.

    Article  Google Scholar 

Download references

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

(2009). Case 34. In: Sun, T. (eds) Atlas of Hematologic Neoplasms. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-89848-3_35

Download citation

  • DOI: https://doi.org/10.1007/978-0-387-89848-3_35

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-89847-6

  • Online ISBN: 978-0-387-89848-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics