Abstract
This chapter will cover one of the most promising and elegant approach for studying the effect of synaptic noise on neurons: the dynamic-clamp injection of artificial conductance-based synaptic noise.We start by an introduction to the dynamic-clamp technique, and we next describe the “re-creation” of in vivo-like activity states in neurons maintained in vitro. We then overview the consequences of synaptic noise on the integrative properties of neurons, as found by dynamic-clamp experiments.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2012 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Destexhe, A., Rudolph-Lilith, M. (2012). Recreating Synaptic Noise Using Dynamic-Clamp. In: Neuronal Noise. Springer Series in Computational Neuroscience, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-79020-6_6
Download citation
DOI: https://doi.org/10.1007/978-0-387-79020-6_6
Published:
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-79019-0
Online ISBN: 978-0-387-79020-6
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)