Abstract
Critical illness polyneuropathy (CIP) and myopathy (CIM) are neuromuscular disorders that have been documented in critically ill patients admitted into intensive care units and are usually noted because of their failure to wean from mechanical ventilation. As a result of the diseases, there are increases in hospitalization length of stay, morbidity, and costs.
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References
Bolton CF. Critical illness polyneuropathy and myopathy. Crit Care Med. 2001;29(12):2388–2390.
de Letter MA, Schmitz PI, Visser LH, et al. Risk factors for the development of polyneuropathy and myopathy in critically ill patients. Crit Care Med. 2001;29(12):2281–2286.
Latronico N. Neuromuscular alterations in the critically ill patient: critical illness myopathy, critical illness neuropathy, or both. Intensive Care Med. 2003;29(9):1411–1413.
De Jonghe B, Sharshar T, Lefaucheur JP, et al. Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA. 2002;288(22):2859–2867.
BednarÃk J, Vondracek P, Dusek L, Moravcova E, Cundrle I. Risk factors for critical illness polyneuromyopathy. J Neurol. 2005;252(3):343–351.
Zochodne DW, Bolton CF, Wells GA. Critical illness polyneuropathy: a complication of sepsis and multiple organ failure. Brain. 1987;110(4):819–841.
Bolton CF. Sepsis and the systemic inflammatory response syndrome: neuromuscular manifestations. Crit Care Med. 1996;24(8):1408–1416.
Hirano M, Ott BR, Raps EC, et al. Acute quadriplegic myopathy: a complication of treatment with steroids, nondepolarizing blocking agents, or both. Neurology. 1992;42(11):2082–2087.
Rich MM, Raps EC, Bird SJ. Distinction between acute myopathy syndrome and critical illness polyneuropathy. Mayo Clin Proc. 1995;70(2):198–200.
Rich MM, Teener JW, Raps EC, Schotland DL, Bird SJ. Muscle is electrically inexcitable in acute quadriplegic myopathy. Neurology. 1996;46(3):731–736.
Rossignol B, Gueret G, Pennec JP, et al. Effects of chronic sepsis on the voltage-gated sodium channel in isolated rat muscle fibers. Crit Care Med. 2007;35(2):351–357.
Young GB. Intensive care unit/critical illness myopathy: toward a unifying hypothesis. Crit Care Med. 2007;35(2):628–629.
Sandrock AW, Cros DP, Louis DN. Case 11-1997 – A 51-year-old man with chronic obstructive pulmonary disease and generalized muscle weakness. N Engl J Med. 1997;336(15):1079.
Khan J, Harrison TB, Rich MM, Moss M. Early development of critical illness myopathy and neuropathy in patients with severe sepsis. Neurology. 2006;67(8):1421–1425.
Latronico N, Bertolini G, Guarneri B, et al. Simplified electrophysiological evaluation of peripheral nerves in critically ill patients: the Italian multi-centre CRIMYNE study. Crit Care. 2007;11(1):R11.
Schweickert WD, Hall J. ICU acquired weakness. Chest. 2007;131:1541–1549.
van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically Ill patients. N Engl J Med. 2001;345(19):1359–1367.
Van den Berghe G, Schoonheydt K, Becx P, Bruyninckx F, Wouters PJ. Insulin therapy protects the central and peripheral nervous system of intensive care patients. Neurology. 2005;64(8):1348–1353.
Visser LH. Critical illness polyneuropathy and myopathy: clinical features, risk factors and prognosis. Eur J Neurol. 2006;13:1203–1212.
Fletcher SN, Kennedy DD, Ghosh IR, et al. Persistent neuromuscular and neurophysiologic abnormalities in long-term survivors of prolonged critical illness. Crit Care Med. 2003;31:1012–1016.
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Henderson, G.V. (2010). Critical Illness Polyneuropathy and Myopathy. In: O’Donnell, J.M., Nácul, F.E. (eds) Surgical Intensive Care Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-77893-8_18
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DOI: https://doi.org/10.1007/978-0-387-77893-8_18
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