Estimation with external information

  • E.W. Steyerberg
Part of the Statistics for Biology and Health book series (SBH)


In this chapter we discuss methods that estimate regression coefficients based on the combination of findings, in the sample under study with external information. We start with a simple “adaptation” method for univariate regression coefficients, which may be obtained from meta-analysis. This method was applied in a case study of operative mortality of abdominal aneurysm surgery. Next, we discuss some alternative approaches to estimate regression coefficients, including Bayesian estimation with explicit prior information.


Prior Distribution Individual Patient Data Adaptation Method Informative Prior Shrinkage Factor 
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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • E.W. Steyerberg
    • 1
  1. 1.Department of Public HealthErasmus MCRotterdamThe Netherlands

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