• Alfredo BerrutiEmail author
  • Paola Sperone
  • Paola Perotti
  • Anna Ferrero
  • Luigi Dogliotti
  • Massimo Terzolo


The extreme rarity of adrenocortical carcinoma (ACC) has hampered the conduction of well-designed high-powered prospective studies testing the efficacy of systemic therapy. This limitation notwithstanding, there is evidence that chemotherapy has some activity in advanced ACC. Patients considered eligible for chemotherapy are generally patients with advanced/inoperable disease progressing with mitotane treatment or patients with ACC demonstrating a rapid pattern of tumor growth.


Adrenocortical Carcinoma Weekly Paclitaxel Disease Response Single Institution Experience Metronomic Chemotherapy 
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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Alfredo Berruti
    • 1
    Email author
  • Paola Sperone
    • 1
  • Paola Perotti
    • 1
  • Anna Ferrero
    • 1
  • Luigi Dogliotti
    • 1
  • Massimo Terzolo
    • 2
  1. 1.Oncologia MedicaAzienda Ospedaliero Universitaria San LuigiOrbassanoItaly
  2. 2.Department of Clinical and Biological Sciences, Medicina lnterna 1, AOU San Luigi GonzagaUniversity of TurinOrbassanoItaly

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