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Taurine 7 pp 47–55Cite as

Modulation by Taurine of Human Arterial Stiffness and Wave Reflection

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Part of the Advances in Experimental Medicine and Biology book series (AEMB,volume 643)

Abstract

Effects of taurine (1000–2000 mg) on hemodynamic function and the arterial pulse wave were investigated for 102 healthy medical and paramedical students. The vascular parameters were generally dependent on aging, with the arterial stiffness parameters, such as baPWV, ABI and AI, are considered the indicators of “vascular aging”. Acute administration of taurine decreased BP and HR and attenuated the stiffness parameters derived from the pulse waveform. Thus, taurine can cause significant changes in the cardiovascular system and the arterial pulse wave. However, approximately 5% of the students were non-responders. This may be related to the notion that taurine would be expected to exert greater effects on the vascular functions of unhealthy individuals. Based our previous experiments, therefore, taurine plays a role in the regulation of the cardiac and vascular function.

Keywords

  • Arterial Stiffness
  • Pulse Wave Velocity
  • Stiffness Parameter
  • Augmentation Index
  • Pulse Waveform

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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  • DOI: 10.1007/978-0-387-75681-3_5
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Author information

Authors and Affiliations

  1. Department of Pharmacology, Nara Medical University Nara and Hyogo NCC College, Hyogo, Japan

    Hiroyasu Satoh

Authors
  1. Hiroyasu Satoh
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  2. Jangmi Kang
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Editor information

Editors and Affiliations

  1. Department Clinical Evaluation of Medicines and Therapeutics, Osaka University, 1–6 Yamada Oka, Suita Osaka, 565-0871 Japan

    Junichi Azuma

  2. Department of Pharmacology College of Medicine, University of South Alabama, 307 University blvd., Mobile, Alabama 36688, USA

    Stephen W. Schaffer

  3. Department of Pharmacology College of Medicine, University of South Alabama, 307 University blvd., Mobile, Alabama 36688, USA

    Takashi Ito

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Satoh, H., Kang, J. (2009). Modulation by Taurine of Human Arterial Stiffness and Wave Reflection. In: Azuma, J., Schaffer, S.W., Ito, T. (eds) Taurine 7. Advances in Experimental Medicine and Biology, vol 643. Springer, New York, NY. https://doi.org/10.1007/978-0-387-75681-3_5

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