Abstract
Electrochemical impedance spectroscopy (EIS) is an important detection technique for biosensors. In the field of immunosensors, and particularly pathogen detection, it is one of the preferred electrochemical techniques because it does away with the use of enzyme labels or redox mediators. This chapter provides an introduction to the fundamentals of EIS and basic data analysis, with an emphasis on the most common features found in immunosensors and possible experimental limitations.
This chapter then discusses a series of functionalisation approaches that can be used in the development of an immunosensor for the detection of bacteria. This is followed by a selection of impedance-based immunosensor examples from the literature.
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References
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Muñoz-Berbel, X., Godino, N., Laczka, O., Baldrich, E., Muñoz, F.X., del Campo, F.J. (2008). Impedance-Based Biosensors for Pathogen Detection. In: Zourob, M., Elwary, S., Turner, A. (eds) Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems. Springer, New York, NY. https://doi.org/10.1007/978-0-387-75113-9_15
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