Abstract
Lactating female rabbits (Oryctolagus cuniculus) nurse once daily for 5 min. The pups are thus forced to localize the nipples quickly. The females emit multiple chemosignals to guide them, among which are common odors derived from dietary aromas and one identified pheromone. Thus, the mammary pheromone (MP) released in rabbit milk is highly behaviorally active: it is a potent releaser of suckling-related behaviors in pups. The MP also acts as a strong reinforcer for early odor learning. Both of these functions of the MP are active right after birth and are thus in a position to play a central role in neonatal adaptation. However, the releasing function and the reinforcing functions of the MP follow different time-courses, suggesting that they are controlled by different underlying mechanisms. These data illustrate how a same chemical signal can carry distinct functions in a newborn mammal.
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References
Bautista, A., Mendoza-Degante, M., Coureaud, G., Martina-Gomez, M., and Hudson, R. (2005) Scramble competition in newborn domestic rabbits for an unusually restricted milk supply. Anim. Behav. 70, 997–1002.
Beauchamp, G.K., Doty, R.L., Moulton, D.G. and Mugford, R.A. (1976) The pheromone concept in mammalian chemical communication. In Doty R.L. (Ed.), Mammalian Olfaction, Reproductive Processes and Behaviour. Academic Press, New York, pp 143–160.
Bilkó, A., Altbäcker, V. and Hudson, R. (1994) Transmission of food preference in the rabbit: The means of information transfer. Physiol. Behav. 56, 907–912.
Bronson, F.H. (1971) Rodent pheromones. Biol. Reprod. 4, 344–357.
Coureaud, G. (2001) Olfactory regulation of sucking in newborn rabbit: Ethological and chemical characterization of a pheromonal signal. PhD Thesis, University of Paris.
Coureaud, G. and Schaal, B. (2000) Attraction of newborn rabbits to abdominal odors of adult conspecifics differing in sex and physiological state. Dev. Psychobiol. 36, 271–281.
Coureaud, G., Langlois, D., Perrier, G. and Schaal B. (2003) A single key-odorant accounts for the pheromonal effect of rabbit milk: Further test of the mammary pheromone’s activity against a wide sample of volatiles from milk. Chemoecology 13, 187–192.
Coureaud, G., Langlois, D., Perrier, G. and Schaal, B. (2006a). Convergent changes in the maternal emission and pup reception of the rabbit mammary pheromone. Chemoecology 16, 169–174.
Coureaud, G., Langlois, D., Sicard, G. and Schaal, B. (2004) Newborn rabbit reactivity to the mammary pheromone: Concentration-response relationship. Chem. Senses 29, 341–350.
Coureaud, G., Montigny, D., Dewas, M., Moncomble, A.S., Patris, P. and Schaal, S. (2005) A sensitive period for pheromone-induced odour learning in newborn rabbits. 29th International Ethological Conference, Budapest, Hungary, 20–27 August.
Coureaud, G., Moncomble, A.S., Montigny, D., Dewas, M., Perrier, G. and Schaal, B. (2006c) A pheromone that rapidly promotes learning in the newborn. Curr. Biol. 16, 1956–1961.
Coureaud, G., Rodel, H.G., Kurz, C., von Holst, D. and Schaal, B. (2006b) Age-related changes in the processing of the rabbit mammary pheromone: comparison in domestic and wild pups. 17th Congress of the European Chemoreception Research Organisation, Granada, Spain, and Chem. Senses 31, 274 (abstract online).
Coureaud, G., Schaal, B., Coudert, P., Rideaud, P., Fortun-Lamothe, L., Hudson, R. and Orgeur, P. (2000) Immediate postnatal sucking in the rabbit: its influence on pup survival and growth. Reprod. Nutr. Dev. 40, 19–32.
Coureaud, G., Schaal, B., Hudson, R., Orgeur, P. and Coudert, P. (2002) Transnatal olfactory continuity in the rabbit: behavioral evidence and short-term consequence of its disruption. Dev. Psychobiol. 40, 372–390.
Coureaud, G., Schaal, B., Langlois, D. and Perrier G (2001) Orientation response of newborn rabbits to odours emitted by lactating females: Relative effectiveness of surface and milk cues. Anim. Behav. 61, 153–162.
Distel, H. and Hudson, R. (1985) The contribution of olfactory and tactile modalities to the performance of nipple-search behaviour in newborn rabbits. J. Comp. Physiol. A 157, 599–605.
Drummond, H. Vázquez, E., Sanchez-Colón, S., Martinez-Gómez, M. and Hudson, R. (2000) Competition for milk in the domestic rabbit: Survivors benefit from littermate deaths. Ethology 106, 511–526.
González-Mariscal, G., Chirino, R. and Hudson, R. (1994) Prolactin stimulates emission of nipple pheromone in ovariectomized New Zealand white rabbits. Biol. Reprod. 50, 373–376.
Hudson, R. and Distel H. (1983) Nipple location by newborn rabbits: behavioural evidence for pheromonal guidance. Behaviour 85, 260–275.
Hudson, R. and Distel, H. (1984) Nipple-search pheromone in rabbits: dependence on season and reproductive state. J. Comp. Physiol. A 155, 13–17.
Hudson, R. and Distel, H. (1986) Pheromonal release of suckling in rabbits does not depend on the vomeronasal organ. Physiol. Behav. 37, 123–129.
Jilge, B. and Hudson, R. (2001) Diversity and development of the circadian rhythms in the European rabbit. Chronobiol. Int. 18, 1–26.
Johnston, R.E. (2000) Chemical communication and pheromones: The types of chemical signals and the role of the vomeronasal system. In Finger T.E., Silver W.L., and Restrepo D. (Eds.), The Neurobiology of Taste and Smell. Wiley-Liss, New York, pp 101–127.
Karlson, P. and Lø‘scher, M. (1959) ’’Pheromones”: a new term for a class of biologically active substances. Nature 183, 55–56.
Keil, W., von Stralendorff, F. and Hudson, R. (1990) A behavioral bioassay for analysis of rabbit nipple-search pheromone. Physiol. Behav. 47, 525–529.
Kindermann, U., Gervais, R. and Hudson, R. (1991) Rapid odor conditioning in newborn rabbits: Amnesic effect of hypothermia. Physiol. Behav. 50, 457–460.
Moncomble, A.S., Coureaud, G., Quennedey, B., Langlois, D., Perrier, G., Brossut, R. and Schaal, B. (2005) The mammary pheromone of the rabbit: where does it come from? Anim. Behav. 69, 29–38.
Montigny, D., Coureaud, G. and Schaal, B. (2005) Circadian and developmental fluctuations in the releasing and reinforcing potencies of the rabbit mammary pheromone. 16th Congress of the European Chemoreception Research Organisation, Dijon, France, and Chem. Senses 30(2), 180 (abstract online).
Montigny, D., Coureaud, G. and Schaal, B. (2006) Newborn rabbit response to the mammary pheromone: From automatism to prandial control. Physiol. Behav. 89, 742–749.
Müller, K. (1978) Zum Saugverhalten von Kaninchen unter besonderer Berücksichtigung des Geruchsvermögens. PhD Thesis, University of Giessen.
Nordlund, D.A. and Lewis W.J. (1976) Terminology of chemical releasing stimuli in intraspecific and interspecific interactions. J. Chem. Ecol. 2, 211–220.
Rosenblatt, J.S. (1983) Olfaction mediates developmental transition in the altricial newborn of selected species of mammals. Dev. Psychobiol. 16, 347–375.
Schaal, B., Coureaud, G., Langlois, D., Giniès, C., Sémon, E. and Perrier, G. (2003) Chemical and behavioural characterization of the rabbit mammary pheromone. Nature 424, 68–72.
Schaal, B., Coureaud, G., Marlier, L. and Soussignan, R. (2001) Fetal olfactory cognition preadapts neonatal behavior in mammals. In Marchlewska-Koj A., Lepri J. and Müller-Schwarze D. (Eds.), Chemical Signals in Vertebrates, Volume 9. Plenum-Klüwer Academic, New York, pp 197–205.
Schley, P. (1981) Olfaction and suckling in young rabbits. Kleintierpraxis 26, 261–263.
Semke E., Distel H. and Hudson, R. (1995) Specific enhancement of olfactory receptor sensitivity associated with foetal learning of food odours in the rabbit. Naturwissenschaften 82, 148–149.
Sullivan, R.M., Hofer, M.A. and Brake, S.C. (1986) Olfactory-guided orientation in neonatal rats is enhanced by a conditioned change in behavioral state. Dev. Psychobiol. 19, 615–623.
Wilson, E.O. and Bossert, W.H. (1963) Chemical communication among animals. Recent Prog. Horm. Res. 19, 673–716.
Zarrow, M. X., Denenberg, V. H. and Anderson, C. O. (1965) Rabbit: frequency of suckling in the pup. Science 150, 1835–1836.
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Coureaud, G., Schaal, B. (2008). Psychobiological functions of the mammary pheromone in newborn rabbits. In: Hurst, J.L., Beynon, R.J., Roberts, S.C., Wyatt, T.D. (eds) Chemical Signals in Vertebrates 11. Springer, New York, NY. https://doi.org/10.1007/978-0-387-73945-8_29
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