Construction of a Coumarin Library for Development of Fluorescent Sensors

  • Tomoya HiranoEmail author
  • Hiroyuki Kagechika
Part of the Integrated Analytical Systems book series (ANASYS)


Construction of chemical libraries is a useful approach to the discovery of better fluorescent materials, and several types, such as styryl dyes and cyanine dyes, have been reported. In this chapter, we focus on construction of a library of chemicals having a coumarin skeleton as the core structure. Coumarin and its derivatives are key structures in various bioactive or fluorescent molecules, and their fluorescence properties are dependent on the precise structure, including the positions of substituents.


Nitric Oxide Coupling Reaction Fluorescence Property Boronic Acid Fluorescent Molecule 
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Copyright information

© Springer Science + Business Media, LLC 2009

Authors and Affiliations

  1. 1.School of Biomedical SciencesTokyo Medical and Dental UniversityTokyoJapan

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