Complications of Sclerotherapy

  • Girish S. Munavalli
  • Robert A. Weiss


Sclerotherapy is the systematic, targeted elimination of intracutaneous and subcutaneous varicose, reticular telangiectasias by the injection of a locally irritating chemical substance, called a sclerosant. Physicians practicing phlebology (the study and science of diagnosis and treatment of veins) rely heavily on the use of sclerotherapy to rid the body of diseased veins. Sclerosants work by direct mechanisms to provoke marked damage of the endothelium of the vessels and possibly transmural wall damage. Subsequently, a local thrombus is generated and, in the long term, damaged veins will be transformed into a fibrous cord, a process referred to as sclerosis. The purpose of sclerotherapy is not just a thrombosis of the vessel, but the definite transformation into a fibrous cord which is impossible to recanalize.1 In essence, the endpoint of this process is functionally analogous to surgical removal of a vein.


Hypertonic Saline Varicose Vein Arterial Injection Sodium Tetradecyl Sulfate Cutaneous Necrosis 
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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Girish S. Munavalli
    • 1
  • Robert A. Weiss
    • 1
    • 2
  1. 1.Department of DermatologyJohns Hopkins University School of MedicineCharlotteUSA
  2. 2.Maryland Laser, Skin, and Vein InstituteHunt ValleyUSA

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