Medical Management of Acute Rhinosinusitis
Broadly defined, acute rhinosinusitis is an inflammatory condition of the nose and paranasal sinuses lasting up to 4 weeks . This straightforward definition does not take into account etiology, which is typically, but not always, infectious. Viruses and bacteria are the most common causes of acute rhinosinusitis, with both resulting from, as well as causing, mucosal thickening and trapped mucous secretions. As a result of the upper and lower airways typically reacting in concert, lower airway inflammation may also be a feature of acute upper airway inflammation. Treatment of acute rhinosinusitis, therefore, is aimed not only at causative organisms, but also at the associated inflammation and resulting symptoms.
Chronic rhinosinusitis, defined as symptoms lasting longer than 12 weeks, is a condition separate from acute rhinosinusitis in etiology and pathophysiology. The syndrome of chronic rhinosinusitis appears to be a primarily inflammatory condition, with intermittent acute...
KeywordsAcute Exacerbation Chronic Rhinosinusitis Macrolide Antibiotic Ipratropium Bromide Moraxella Catarrhalis
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