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References
USRDS. USRDS 2005 Annual Data Report: Atlas of End-Stage Renal Disease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. 2005.
Standards of medical care in diabetes—2006. Diabetes Care 2006; 29(Suppl 1): S4–42.
Caramori, M.L., Fioretto, P., Mauer, M. Enhancing the predictive value of urinary albumin for diabetic nephropathy. J. Am. Soc. Nephrol. 2006; 17(2):339–352.
Hovind, P., Tarnow, L., Rossing, P., et al. Predictors for the development of microalbuminuria and macroalbuminuria in patients with type 1 diabetes: Inception cohort study. BMJ 2004; 328(7448):1105.
Mogensen, C.E., Christensen, C.K. Predicting diabetic nephropathy in insulin-dependent patients. N. Engl. J. Med. 1984; 311(2):89–93.
Tognoni, G. Report on management of renal failure in Europe, XXVI, 1995. A conceptual and practical framework for interactive use of the ERA-EDTA Registry. Nephrol. Dial. Transplant 1996;11(Suppl)7:1–3.
Leon, C.A., Raij, L. Interaction of haemodynamic and metabolic pathways in the genesis of diabetic nephropathy. J. Hypertens. 2005; 23(11):1931–1937.
Lightstone, L., Rees, A.J., Tomson, C., Walls, J., Winearls, C.G., Feehally, J. High incidence of end-stage renal disease in Indo-Asians in the UK. Quar. J. Med. 1995; 88(3):191–195.
Rich, S.S. Genetics of diabetes and its complications. J. Am. Soc. Nephrol. 2006; 17(2):353–360.
Fioretto, P., Steffes, M.W., Barbosa, J., Rich, S.S., Miller, M.E., Mauer, M. Is diabetic nephropathy inherited? Studies of glomerular structure in type 1 diabetic sibling pairs. Diabetes 1999; 48(4):865–869.
Langefeld, C.D., Beck, S.R., Bowden, D.W., Rich, S.S., Wagenknecht, L.E., Freedman, B.I. Heritability of GFR and albuminuria in Caucasians with type 2 diabetes mellitus. Am. J. Kidney Dis. 2004; 43(5):796–800.
Susztak, K., Bottinger, E.P. Diabetic nephropathy: A frontier for personalized medicine. J. Am. Soc. Nephrol. 2006; 17(2):361–367.
Jones, S.L., Wiseman, M.J., Viberti, G.C. Glomerular hyperfiltration as a risk factor for diabetic nephropathy: Five-year report of a prospective study. Diabetologia 1991; 34(1):59–60.
Caramori, M.L., Fioretto, P., Mauer, M. Low glomerular filtration rate in normoalbuminuric type 1 diabetic patients: An indicator of more advanced glomerular lesions. Diabetes 2003; 52(4):1036–1040.
Klein, R., Zinman, B., Gardiner, R., et al. The relationship of diabetic retinopathy to preclinical diabetic glomerulopathy lesions in type 1 diabetic patients: The Renin-Angiotensin System Study. Diabetes 2005; 54(2):527–533.
Effect of intensive therapy on the development and progression of diabetic nephropathy in the Diabetes Control and Complications Trial. The Diabetes Control and Complications (DCCT) Research Group. Kidney Int. 1995; 47(6):1703–1720.
Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: The Epidemiology of Diabetes Interventions and Complications (EDIC) study. JAMA 2003; 290(16):2159–2567.
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998; 352(9131):837–853.
Perkins, B.A., Ficociello, L.H., Silva, K.H., Finkelstein, D.M., Warram, J.H., Krolewski, A.S. Regression of microalbuminuria in type 1 diabetes. N. Engl. J. Med. 2003; 348(23):2285–2293.
Araki, S., Haneda, M., Sugimoto, T., et al. Factors associated with frequent remission of microalbuminuria in patients with type 2 diabetes. Diabetes 2005; 54(10):2983–2987.
Giorgino, F., Laviola, L., Cavallo Perin, P., Solnica, B., Fuller, J., Chaturvedi, N. Factors associated with progression to macroalbuminuria in microalbuminuric type 1 diabetic patients: The EURODIAB Prospective Complications Study. Diabetologia 2004; 47(6):1020–1028.
Lurbe, E., Redon, J., Kesani, A., et al. Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes. N. Engl. J. Med. 2002; 347(11):797–805.
Nelson, R.G., Pettitt, D.J., Baird, H.R., et al. Pre-diabetic blood pressure predicts urinary albumin excretion after the onset of type 2 (non-insulin-dependent) diabetes mellitus in Pima Indians. Diabetologia 1993; 36(10):998–1001.
Chase, H.P., Garg, S.K., Marshall, G., et al. Cigarette smoking increases the risk of albuminuria among subjects with type I diabetes. JAMA 1991; 265(5):614–617.
Baggio, B., Budakovic, A., Dalla Vestra, M., Saller, A., Bruseghin, M., Fioretto, P. Effects of cigarette smoking on glomerular structure and function in type 2 diabetic patients. J. Am. Soc. Nephrol. 2002; 13(11):2730–2736.
Lin, J., Hu, F.B., Rimm, E.B., Rifai, N., Curhan, G.C. The association of serum lipids and inflammatory biomarkers with renal function in men with type II diabetes mellitus. Kidney Int. 2006; 69(2):336–342.
Mogensen, C.E., Schmitz, A., Christensen, C.K. Comparative renal pathophysiology relevant to IDDM and NIDDM patients. Diabetes Metab. Rev. 1988; 4(5):453–483.
Kramer, H.J., Nguyen, Q.D., Curhan, G., Hsu, C.Y. Renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetes mellitus. JAMA 2003; 289(24):3273–3277.
Eknoyan, G., Hostetter, T., Bakris, G.L., et al. Proteinuria and other markers of chronic kidney disease: A position statement of the National Kidney Foundation (NKF) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Am. J. Kidney Dis. 2003; 42(4):617–622.
K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Am. J. Kidney Dis. 2002; 39(2 Suppl 1):S1–266.
Striker LJS, G., D’ Agati, V. The Renal Biopsy, 3rd ed. Philadelphia: W.B. Saunders Company. 1997.
Brownlee, M. The pathobiology of diabetic complications: A unifying mechanism. Diabetes 2005; 54(6):1615–1625.
Ziyadeh, F.N., Sharma, K., Ericksen, M., Wolf, G. Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta. J. Clin. Invest. 1994; 93(2):536–542.
Williams, M.E., Tuttle, K.R. The next generation of diabetic nephropathy therapies: An update. Adv. Chronic Kidney Dis. 2005; 12(2):212–222.
Fornoni, A., Lenz, O., Striker, L.J., Striker, G.E. Glucose induces clonal selection and reversible dinucleotide repeat expansion in mesangial cells isolated from glomerulosclerosis-prone mice. Diabetes 2003; 52(10):2594–2602.
Gnudi, L., Viberti, G., Raij, L., et al. GLUT-1 overexpression: Link between hemodynamic and metabolic factors in glomerular injury? Hypertension 2003; 42(1):19–24.
Carmines, P.K., Ohishi, K., Ikenaga, H. Functional impairment of renal afferent arteriolar voltage-gated calcium channels in rats with diabetes mellitus. J. Clin. Invest. 1996; 98(11):2564–2571.
Galkina, E., Ley, K. Leukocyte recruitment and vascular injury in diabetic nephropathy. J. Am. Soc. Nephrol. 2006; 17(2):368–377.
Lewis, E.J., Hunsicker, L.G., Bain, R.P., Rohde, R.D. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. N. Engl. J. Med. 1993; 329(20):1456–1462.
Bakris, G.L., Williams, M., Dworkin, L., et al. Preserving renal function in adults with hypertension and diabetes: A consensus approach. National Kidney Foundation Hypertension and Diabetes Executive Committees Working Group. Am. J. Kidney Dis. 2000; 36(3):646–661.
Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: Results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators. Lancet 2000; 355(9200):253–259.
Parving, H.H., Lehnert, H., Brochner-Mortensen, J., Gomis, R., Andersen, S., Arner, P. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N. Engl. J. Med. 2001; 345(12):870–878.
Brenner, B.M., Cooper, M.E., de Zeeuw, D., et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N. Engl. J. Med. 2001; 345(12):861–869.
Lewis, E.J., Hunsicker, L.G., Clarke, W.R., et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N. Engl. J. Med. 2001; 345(12):851–860.
Hou, F.F., Zhang, X., Zhang, G.H., et al. Efficacy and safety of benazepril for advanced chronic renal insufficiency. N. Engl. J. Med. 2006; 354(2):131–140.
Barnett, A.H., Bain, S.C., Bouter, P., et al. Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy. N. Engl. J. Med. 2004; 351(19):1952–1961.
Chobanian, A.V., Bakris, G.L., Black, H.R., et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003; 42(6):1206–1252.
Ruggenenti, P., Fassi, A., Ilieva, A.P., et al. Preventing microalbuminuria in type 2 diabetes. N. Engl. J. Med. 2004; 351(19):1941–1951.
Gaede, P., Vedel, P., Larsen, N., Jensen, G.V., Parving, H.H., Pedersen, O. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N. Engl. J. Med. 2003; 348(5):383–393.
Brown, A.F., Mangione, C.M., Saliba, D., Sarkisian, C.A. Guidelines for improving the care of the older person with diabetes mellitus. J. Am. Geriatr. Soc. 2003; 51(5 Suppl Guidelines):S265–280.
Wolfe, R.A., Port, F.K., Hawthorne, V.M., Guire, K.E. A comparison of survival among dialytic therapies of choice: In-center hemodialysis versus continuous ambulatory peritoneal dialysis at home. Am. J. Kidney Dis. 1990; 15(5):433–440.
Held, P.J., Port, F.K., Turenne, M.N., Gaylin, D.S., Hamburger, R.J., Wolfe, R.A. Continuous ambulatory peritoneal dialysis and hemodialysis: Comparison of patient mortality with adjustment for comorbid conditions. Kidney Int. 1994; 45(4):1163–1169.
Vonesh, E.F., Snyder, J.J., Foley, R.N., Collins, A.J. The differential impact of risk factors on mortality in hemodialysis and peritoneal dialysis. Kidney Int. 2004; 66(6):2389–2401.
Brunner, F.P., Selwood, N.H. Profile of patients on RRT in Europe and death rates due to major causes of death groups. The EDTA Registration Committee. Kidney Int. Suppl. 1992; 38:S4–15.
Konner, K., Hulbert-Shearon, T.E., Roys, E.C., Port, F.K. Tailoring the initial vascular access for dialysis patients. Kidney Int. 2002; 62(1):329–338.
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Fornoni, A., Leon, C., Raij, L. (2008). Diabetic Nephropathy. In: MachasNúñez, J.F., Cameron, J.S., Oreopoulos, D.G. (eds) The Aging Kidney in Health and Disease. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-72659-5_18
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DOI: https://doi.org/10.1007/978-0-387-72659-5_18
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