Abstract
The establishment of a complete human genome sequence has opened a new era in biology referred to as omics. The term designates a complete analysis of biologic systems in which entire metabolic pathways are studied. This new methodologic approach becomes possible because of the dynamic development of advanced instrumentation unique for each of the omics subdisciplines. By increasing analytical sensitivity and through transformation into high-throughput analysis, such technologies as DNA and protein microarray or mass spectrometry have become a driving force for omics research. The amount of information derived from omics disciplines has in turn stimulated the development of bioinformatics. By improving the methods of storage and analysis of large amounts of data, an improved system of bioinformatics allows efficient exchange of information among researchers and contributes significantly to the development of omics disciplines. Despite its short history, this new methodology has proved its effectiveness by advancing our understanding of biologic processes, which brings hope for more accurate diagnosis and treatment of diseases.
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Fowler, L., Furmaga, W. (2008). Proteomics. In: Zander, D.S., Popper, H.H., Jagirdar, J., Haque, A.K., Cagle, P.T., Barrios, R. (eds) Molecular Pathology of Lung Diseases. Molecular Pathology Library, vol 1. Springer, New York, NY. https://doi.org/10.1007/978-0-387-72430-0_13
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DOI: https://doi.org/10.1007/978-0-387-72430-0_13
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