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Iodinated Liposomes as Contrast Agents

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Nanoparticles in Biomedical Imaging

Part of the book series: Fundamental Biomedical Technologies ((FBMT,volume 102))

Abstract

The use of liposomal contrast agents for computed tomography (CT) imaging applications is considered. The properties of the various liposome types as well as methods for their preparation are discussed. Specific challenges for the preparation and use of CT contrast-carrying liposomes are outlined. Available experience on the use of CT liposomes for liver and spleen imaging in preclinical animal models and humans is reviewed. The use of surface-modified and conventional liposomes for CT blood-pool imaging is discussed in light of the published animal data. Finally, new trends in the use of CT liposomes are considered based on the limited data available to date.

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Authors
  1. Andreas Sachse
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Editor information

Editors and Affiliations

  1. Department of Radiology, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, 21205

    Jeff W.M. Bulte

  2. Institute of Psychiatry King’s College London, Center for the Cellular Basis of Behaviour, 125 Coldharbour Lane, London SE5 9NU, United Kingdom

    Michel M.J. Modo

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Sachse, A. (2008). Iodinated Liposomes as Contrast Agents. In: Bulte, J.W., Modo, M.M. (eds) Nanoparticles in Biomedical Imaging. Fundamental Biomedical Technologies, vol 102. Springer, New York, NY. https://doi.org/10.1007/978-0-387-72027-2_18

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