Acoustic Neuromas and Other Benign Tumors: Fractionated Stereotactic Radiotherapy Perspective

  • David W. Andrews
  • Greg Bednarz
  • Beverly Downes
  • Maria Werner-Wasik


Radiosurgery has become an important treatment alternative to surgery for a variety of intracranial lesions. As currently practiced, it has in fact replaced surgery as a standard of care in some instances, complements surgery as a postoperative adjunct in others, and most commonly represents an alternative to surgery or the only treatment option. Radiosurgery techniques have evolved quickly with the development of new technologies enabling more complex yet more efficient treatment plans. As a consequence, these technologies have broadened radiosurgery applications and improved radiosurgery outcomes. Among these newer techniques, treatments involving fractionated stereotactic radiation referred to as fractionated stereotactic radiotherapy, or FSR, have emerged as a consequence of linear accelerators designed for and dedicated to stereotactic techniques. Without the logistical constraints of retrofitted general-purpose linear accelerators used in radiation oncology, often available only once or twice a week, dedicated units have enabled the design of treatment paradigms that strive for an ideal treatment based on the radiobiology of the target and dose-limiting contiguous tissues. This chapter will summarize our 12-year experience with the Varian 600SR, initially with the Radionics software more recently modified to a Novalis shapedbeam radiosurgery unit, and our practice of FSR for a variety of intracranial lesions.


Radiat Oncol Biol Phys Gamma Knife Acoustic Neuroma Cochlear Nerve Tumor Control Rate 
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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • David W. Andrews
    • 1
  • Greg Bednarz
    • 2
  • Beverly Downes
    • 3
  • Maria Werner-Wasik
    • 4
  1. 1.Division of Neuro-Oncologic Neurosurgery & Stereotactic RadiosurgeryThomas Jefferson UniversityPhiladelphiaUSA
  2. 2.Department of Radiation OncologyThomas Jefferson University, Jefferson Hospital for NeurosciencePhiladelphiaUSA
  3. 3.Stereotactic Radiosurgery UnitsJefferson Hospital for NeurosciencePhiladelphiaUSA
  4. 4.Department of Radiation OncologyJefferson Hospital for NeurosciencePhiladelphiaUSA

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