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CyberKnife Radiosurgery

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Principles and Practice of Stereotactic Radiosurgery

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Abstract

Conceptually, the lineage of CyberKnife (Accuray Inc., Sunnyvale, CA) technology derives from the clinical principles that underlie stereotactic radiosurgery. This minimally invasive procedure involves the precise delivery of large doses of ionizing radiation to destroy well-defined targets without injuring the surrounding and intervening healthy tissue. This objective is achieved using large numbers of narrow beams that emanate from a wide array of directions and intersect (and therefore accumulate) within the volume selected for ablation. The cumulative dose that can be administered this way overwhelms any capacity for cellular repair, thereby typically ensuring tissue destruction.

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Author information

Authors and Affiliations

  1. Stanford University Medical Center, Stanford, CA, USA

    John R. Adler Jr. MD (Professor of Neurosurgery and Attending Neurosurgeon)

  2. CyberKnife Center Munich, Munich, Germany

    Alexander Muacevic MD

  3. Department of Neurology, State University of New York, Stony Brook, NY, USA

    Pantaleo Romanelli MD (Clinical Assistant Professor, Consulting Assistant Professor and Director)

  4. Department of Neurosurgery, Stanford University, Stanford, CA, USA

    Pantaleo Romanelli MD (Clinical Assistant Professor, Consulting Assistant Professor and Director)

  5. Functional Neurosurgery, Department of Neurosurgery, IRCCS Neuromed, Pozzilli, Italy

    Pantaleo Romanelli MD (Clinical Assistant Professor, Consulting Assistant Professor and Director)

Authors
  1. John R. Adler Jr. MD
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  2. Alexander Muacevic MD
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  3. Pantaleo Romanelli MD
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Editor information

Editors and Affiliations

  1. Department of Neurosurgery, Boston University School of Medicine, Boston, MA, USA

    Lawrence S. Chin MD (Professor and Chairman) (Professor and Chairman)

  2. Department of Radiation Oncology, University of Maryland Medical School, Baltimore, MD, USA

    William F. Regine MD (Professor and Chairman) (Professor and Chairman)

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© 2008 Springer Science+Business Media, LLC

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Adler, J.R., Muacevic, A., Romanelli, P. (2008). CyberKnife Radiosurgery. In: Chin, L.S., Regine, W.F. (eds) Principles and Practice of Stereotactic Radiosurgery. Springer, New York, NY. https://doi.org/10.1007/978-0-387-71070-9_13

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  • DOI: https://doi.org/10.1007/978-0-387-71070-9_13

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-71069-3

  • Online ISBN: 978-0-387-71070-9

  • eBook Packages: MedicineMedicine (R0)

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