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Brain Metastases: Epidemiology and Pathophysiology

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Brain Metastases

Part of the book series: Cancer Treatment and Research ((CTAR,volume 136))

Abstract

Brain metastases are a devastating complication of systemic cancer. Although they typically occur late in the course of the disease, their symptoms of seizures, paralysis and cognitive failure have a major negative impact on quality of life and, once detected, they portend a poor prognosis. Most patients die within months, either from the brain metastasis itself, or if that can be controlled, from widespread systemic disease. Recent data suggest a rise in the incidence of brain metastases [1], so that clinicians face mounting challenges in caring for these patients.

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Sul, J., Posner, J.B. (2007). Brain Metastases: Epidemiology and Pathophysiology. In: Raizer, J.J., Abrey, L.E. (eds) Brain Metastases. Cancer Treatment and Research, vol 136. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-69222-7_1

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