Abstract
Advances in genetics and neuroimaging have revolutionized the diagnosis of intracranial disease in children. An integrated approach to these diseases has also emerged from the proliferation of multidisciplinary clinics and programs combining expertise in pediatric neurology, neurosurgery, neuropathology, neuroradiology, neuro-oncology, and neuro-ophthalmology. The role of genetic defects is increasingly recognized in many intracranial disorders, and basic research elucidates their pathogenesis at the molecular level. Refinement in neurosurgical management continues to advance the treatment of these disorders, while preventative and therapeutic measures will arise from molecular genetic research.
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Brodsky, M.C. (2010). Neuro-Ophthalmologic Manifestations of Systemic and Intracranial Disease. In: Pediatric Neuro-Ophthalmology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-69069-8_11
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