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Chronic Rhinosinusitis in Adults

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Abstract

A computerized PubMed search of MEDLINE 1966-April 2006 was performed. Articles mapping to the medical subject heading “sinusitis” and textwords “chronic” or “recurrent” were obtained, yielding 2503 studies. These articles were then cross-referenced with those publications mapping to the medical subject headings “anti-bacterial agents” or “quinolones” or “penicillins” or “macrolides” or “cephalosporins” or “clindamycin” or the textwords “antibiotics” or “antimicrobials.” This search strategy yielded 447 articles. These publications were then reviewed to identify those that met the following inclusion criteria: 1) adult patient population (>15 years old) with chronic or recurrent rhinosinusitis, 2) intervention with comparative oral antibiotic regimens, 3) outcome measured in terms of clinical improvement, 4) randomized controlled trials (RCTs). Articles focusing only on patients with acute rhinosinusitis were excluded.

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    Article  CAS  PubMed  Google Scholar 

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    CAS  PubMed  Google Scholar 

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    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, MA, USA

    Stacey Gray MD, Ralph Metson MD (Professor) & Gregory W. Randolph MD (Associate Professor)

  2. Harvard Program in Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, MA, USA

    Jennifer J. Shin MD

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  1. Stacey Gray MD
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  2. Jennifer J. Shin MD
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  3. Ralph Metson MD
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  4. Gregory W. Randolph MD
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Editor information

Editors and Affiliations

  1. Harvard Program in Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA

    Jennifer J. Shin MD

  2. Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA

    Christopher J. Hartnick MD, MSE

  3. Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA

    Gregory W. Randolph MD (Pediatric Otolaryngology) (Pediatric Otolaryngology)

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© 2008 Springer Science+Business Media, LLC

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Gray, S., Shin, J.J., Metson, R., Randolph, G.W. (2008). Chronic Rhinosinusitis in Adults. In: Shin, J.J., et al. Evidence-Based Otolaryngology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-49979-6_22

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  • DOI: https://doi.org/10.1007/978-0-387-49979-6_22

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-24447-1

  • Online ISBN: 978-0-387-49979-6

  • eBook Packages: MedicineMedicine (R0)

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