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Technological Platforms for Microarray Gene Expression Profiling

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Microarray Technology and Cancer Gene Profiling

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 593))

Abstract

By using gene microarray technology, scientists can determine in a single experiment, the expression levels of thousands of genes within a given sample. DNA microarray technology is evolving rapidly and there are now numerous high-density platforms available which differ in terms of probe content, design, deposition technology, labeling and hybridization protocols. However, two major platforms for high-density microarray manufacture are in common use. The first utilizes robotic deposition or “spotting” of DNA molecules, while the second uses short oligonudeotides synthesized in situ.

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© 2007 Landes Bioscience and Springer Science+Business Media

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Mandruzzato, S. (2007). Technological Platforms for Microarray Gene Expression Profiling. In: Mocellin, S. (eds) Microarray Technology and Cancer Gene Profiling. Advances in Experimental Medicine and Biology, vol 593. Springer, New York, NY. https://doi.org/10.1007/978-0-387-39978-2_2

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