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Sentinel Lymph Node Biopsy in Gynecologic Malignancies

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Radioguided Surgery

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Abstract

Lymph node status is one of the most relevant factors for prognostic and therapeutic strategies for every cancer. It is a powerful predictor of survival in patients with early malignant tumors of the vulva, cervix, and uterus (1). For most cancers, the standard therapeutic approach consists of radical resection of the primary tumor with extensive lymphadenectomy. Malignant diseases require appropriate staging to ensure that the surgery does not exceed the minimum required (2). However, preoperative evaluation of lymph node status to establish the optimal extent of surgical dissection is difficult. It is well known that incorrect staging can affect short- and long-term morbidity and mortality.

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Author information

Authors and Affiliations

  1. Division of Nuclear Medicine, National Cancer Institute, Milan, Italy

    Emilio Bombardieri MD & Marco Maccauro MD

  2. Division of Gynecologic Oncology, National Cancer Institute, Milan, Italy

    Rosanna Fontanelli MD & Francesco Raspagliesi MD

  3. Division of Nuclear Medicine, European Institute of Oncology, Milan, Italy

    Giovanni Paganelli MD

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  1. Emilio Bombardieri MD
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  2. Marco Maccauro MD
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  3. Rosanna Fontanelli MD
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  4. Francesco Raspagliesi MD
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  5. Giovanni Paganelli MD
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Editors and Affiliations

  1. Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy

    Giuliano Mariani MD

  2. John Wayne Cancer Institute, Saint John’s Health Center, Santa Monica, California, USA

    Armando E. Giuliano MD (Chief of Science and Medicine) (Chief of Science and Medicine)

  3. Nuclear Medicine Service, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA

    H. William Strauss MD

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Bombardieri, E., Maccauro, M., Fontanelli, R., Raspagliesi, F., Paganelli, G. (2008). Sentinel Lymph Node Biopsy in Gynecologic Malignancies. In: Mariani, G., Giuliano, A.E., Strauss, H.W. (eds) Radioguided Surgery. Springer, New York, NY. https://doi.org/10.1007/978-0-387-38327-9_13

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  • DOI: https://doi.org/10.1007/978-0-387-38327-9_13

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