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A Template-Based Mixed-Integer Linear Programming Sequence Alignment Model

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Book cover Models and Algorithms for Global Optimization

Part of the book series: Optimization and Its Applications ((SOIA,volume 4))

Abstract

The similarity of DNA or protein sequences between species is an approximate measure of the evolutionary distance between them. By identifying and aligning pairs of sequences, knowledge of the genetic importance of a gene or protein of one species can be extended to a second, relatively unknown species with a similar sequence.

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McAllister, S.R., Rajgaria, R., Floudas, C.A. (2007). A Template-Based Mixed-Integer Linear Programming Sequence Alignment Model. In: Törn, A., Žilinskas, J. (eds) Models and Algorithms for Global Optimization. Optimization and Its Applications, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-36721-7_21

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