Skip to main content

Summary

Exposure to irritant gases usually causes pulmonary symptoms and disease from generation of reactive species. Patients with known or suspected exposure should be observed for >24–48 hours for the development of noncardiogenic pulmonary edema. Treatment in general is supportive with emphasis on improving bronchial airflow and optimizing oxygenation. Corticosteroids may be beneficial for prevention of bronchiolitis obliterans in those exposed to nitrogen dioxide.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ainslie G. 1993. Inhalation injuries produced by smoke and nitrogen dioxide. Respir Med 87:169–174.

    Article  PubMed  CAS  Google Scholar 

  • Anonymous. 2002. Chemical Terrorism Fact Sheet. http://www.bioterrorism.slu.edu. St Louis University.

    Google Scholar 

  • ATSDR medical management guidelines (MMGs) for nitrogen oxides. www.atsdr.cdc.gov/MHMI.

    Google Scholar 

  • Douglas WW, Hepper NG, Colby TV. 1989. Silo-filler’s disease. Mayo Clinic Proc 64(3):291–304.

    CAS  Google Scholar 

  • Mayorga M. 1994. Overview of nitrogen dioxide effects on the lung with emphasis on military relevance. Toxicology 89:175–92.

    Article  PubMed  CAS  Google Scholar 

  • Medical management guidelines for phosgene. ATSDR. http://www.atsdr.cdc.gov/MHMI/ mmg176.html.

    Google Scholar 

  • Nelson LS. 2002. Simple asphyxiants and pulmonary irritants. In Goldfrank’s toxicologic emergencies, 7th ed., pp. 1453–1469. Ed LR Goldfrank, NE Flomenbaum, NA Lewin, MA Howland, RS Hoffman, LS Nelson. New York: McGraw-Hill.

    Google Scholar 

  • Peterson JS, Cairns CB. 2003. Toxicity, nitrous dioxide. www.emedicine.com/emerg/ topic847.htm.

    Google Scholar 

  • Roberge RJ. 2004. Toxicity, chlorine gas. http://www.emedicine.com/EMERG/topic851.htm 2004 Jun 29.

    Google Scholar 

  • Segal E, Lang E. 2004. Toxicity, chlorine gas. http://www.emedicine.com/emerg/topic851.htm.

    Google Scholar 

  • Suchard JR. 2002. Chemical and biologic weapons. In Goldfrank’s toxicologic emergencies, 7th ed., pp. 1527–1552. Ed LR Goldfrank, NE Flomenbaum, NA Lewin, MA Howland, RS Hoffman, LS Nelson. New York: McGraw-Hill.

    Google Scholar 

  • Traub SJ, Hoffman RS, Nelson LS. 2002. Case report and literature review of chlorine gas toxicity. Vet Human Toxicol 44(4):235–239.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer Science +Business Media, LLC

About this chapter

Cite this chapter

Geib, AJ., Burns, M.M. (2006). Pulmonary Agents. In: Antosia, R.E., Cahill, J.D. (eds) Handbook of Bioterrorism and Disaster Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-32804-1_38

Download citation

Publish with us

Policies and ethics