Abstract
The hallmark of a true positive ICC reaction is heterogeneous distribution of crisp granular staining within single cells or among a group of cells. Depending on the antigen, the reaction may be seen on the cell membrane, occupy the entire cytoplasm, be limited to the perinuclear area, or appear intranuclear. With rare exceptions, diffuse monotonous pale brown staining of cells is in all likelihood nonspecific.
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© 2007 Springer Science+Business Media, LLC
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(2007). Evaluation of Results. In: Ganjei-Azar, P., Nadji, M. (eds) Color Atlas of Immunocytochemistry in Diagnostic Cytology. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-32122-6_3
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DOI: https://doi.org/10.1007/978-0-387-32122-6_3
Publisher Name: Springer, Boston, MA
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