Population genetics theory was initially developed, in the 1920’s and 1930’s, by Fisher, Haldane and Wright, and current theory still bears the imprint of the work of these three great masters. Indeed, so fundamental was their contribution that even today, it is difficult to move forward from the paradigms that they introduced. Such a move forward is, however, necessary, especially because of the availability of data from the human genome project and other genome projects, and the need to analyze these data using population genetic theory methods.
KeywordsEffective Population Size Random Mating Historical Background Additive Genetic Variance Darwinian Theory
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