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Helicobacter pylori

  • Sharon Perry
  • Catherine de Martel
  • Julie Parsonnet
Chapter

Helicobacter pylori, a corkscrew-shaped, gram-negative rod, resides in the mucous layer of the human stomach. Unrecognized until the 1980s, the organism is extraordinarily common, infecting at least half of the world’s population. Once acquired, infection persists chronically, typically continuing in the stomach throughout the host’s life. H. pylori infection invariably causes acute and chronic gastric inflammation, but in only a minority of cases does it result in overt clinical disease. Yet, the diseases attributed to H. pylori infection, peptic ulcer disease and gastric malignancy, are among the world’s most important causes of morbidity and mortality in adults. For this reason, the past 30 years have borne witness to furious activity concerning diagnosis, treatment, and prevention of this recently rediscovered pathogen.

Keywords

Gastric Cancer Pylorus Infection Peptic Ulcer Disease Pylorus Eradication Breath Test 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The authors would like to thank Jeremy Schneider and Luz Sanchez for their technical assistance.

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Sharon Perry
    • 1
  • Catherine de Martel
    • 2
  • Julie Parsonnet
    • 3
  1. 1.Department of MedicineStanford University School of MedicineCaliforniaUSA
  2. 2.Department of MedicineStanford University School of MedicineCaliforniaUSA
  3. 3.Department of MedicineStanford University School of MedicineCaliforniaUSA

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