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Syndromes of Extreme Insulin Resistance

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Principles of Diabetes Mellitus

Abstract

This group of syndromes shares severe insulin resistance and hyperinsulinemia with variable clinical manifestations.1,2 Attention has been paid to these rare disorders because they provide insight into several aspects of insulin action at the molecular level and advance our understanding of the more common insulin-resistant disorders, such as polycystic ovarian syndrome3 and type 2 diabetes mellitus.4

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Authors and Affiliations

  1. Grunberger Diabetes Institute, Wayne State University School of Medicine, Detroit, MI, USA

    George Grunberger

  2. Division of Endocrinology and Metabolism, Beth Israel Medical Center, New York, NY, USA

    Bianca Alfonso M.D

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  1. George Grunberger
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  2. Bianca Alfonso M.D
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Correspondence to George Grunberger .

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  1. Div. Endocrinology & Metabolism, Beth Israel Medical Center, East 17th Street 317, New York, 10003, U.S.A.

    Leonid Poretsky

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Grunberger, G., Alfonso, B. (2010). Syndromes of Extreme Insulin Resistance. In: Poretsky, L. (eds) Principles of Diabetes Mellitus. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-09841-8_17

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