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Infant Morbidity

  • Melisa M. AdamsEmail author
Chapter

While epidemiologic research occasionally results in identification of novel associations between exposures and disease, more often it is the astute clinician who makes the initial observations that begin the process. Such was the case in the late 1950s, when a German pediatrician, Dr. Widikund Lenz, began to observe a very unusual pattern of birth defects involving phocomelia. Fetuses affected by this extremely rare condition have limb reduction defects including the absence of hands and/or feet, together with other abnormalities. Dr. Lenz queried colleagues, and compiled a case series with more than 50 cases by late 1961. The common exposure was the use of a new anti-nausea medication, thalidomide. Additional studies demonstrated the power teratogenic effect of this drug, and the timing of fetal development during which its effects were most pronounced. Thalidomide was removed for the market for several decades, but is now prescribed for patients suffering terminal illness.

Rajkumar (

Keywords

Neonatal Intensive Care Unit Birth Certificate Congenital Toxoplasmosis Congenital Rubella Syndrome Congenital Syphilis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

BPD

bronchopulmonary dysplasia

CDC

Centers for Disease Control and Prevention

CMV

cytomegalovirus

CRS

congenital rubella syndrome

CSHCN

Children with Special Health Care Needs

DTP

diphtheria-tetanus-pertussis

GBS

Group B Streptococcus

IUGR

intrauterine growth restriction

IVH

intraventricular hemorrhage

NEC

necrotizing enterocolitis

PKU

phenylketonuria

PVL

periventricular leukomalacia

ROP

retinopathy of prematurity

RSV

retrosynctial virus

SGA

small-for-gestational age

NICU

neonatal intensive care unit

WIC

Special Supplemental Food Program for Women, Infants and Children

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.AtlantaUSA

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