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Neuroprotection Becomes Reality

Changing times for cerebral resuscitation

  • Conference paper
Brain Death and Disorders of Consciousness

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 550))

Abstract

Sudden cardiac arrest (CA) is a leading cause of death worldwide, claiming over 1000 lives daily in the United States. Despite cardiopulmonary resuscitation (CPR) being one of the most dramatic and widely known medical procedures, its overall result remains unsatisfactory. One third of CPRs succeed in restoring spontaneous perfusion, but less than half of those patients ever regain consciousness, and less than 10 per cent of survivors can return to their former lifestyle.1–4 The results of CPR are particularly dismal in subgroups such as the elderly or patients with primary asystole. Severe brain damage is the prime cause of death and disability in these patients, due to the exquisite sensitivity of the brain to anoxia.

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Author information

Authors and Affiliations

  1. Department of Neurology, University Hospitals of Leicester, UK

    Maxwell S. Damian MD.

Authors
  1. Maxwell S. Damian MD.
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Editor information

Editors and Affiliations

  1. Institute of Neurology and Neurosurgery, Havana, Cuba

    Calixto Machado

  2. David Geffen School of Medicine at UCLA, Los Angeles, California, USA

    D. Alan Shewmon

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© 2004 Springer Science+Business Media New York

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Damian, M.S. (2004). Neuroprotection Becomes Reality. In: Machado, C., Shewmon, D.A. (eds) Brain Death and Disorders of Consciousness. Advances in Experimental Medicine and Biology, vol 550. Springer, Boston, MA. https://doi.org/10.1007/978-0-306-48526-8_12

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  • DOI: https://doi.org/10.1007/978-0-306-48526-8_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-0976-6

  • Online ISBN: 978-0-306-48526-8

  • eBook Packages: Springer Book Archive

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