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References
Parkin DM, Pisani P, Ferlay J (1990) Estimates of the worldwide incidence of 25 major cancers in 1990. Int J Cancer 80:827–841
Taura N, Hamasaki K, Nakao K et al (2005) Clinical benefits of hepatocellular carcinoma surveillance: A single-center, hospital-based study. Oncol Rep 14:999–1003
Sala M, Llovet JM, Vilana R et al (2004) Initial response to percutaneous ablation predicts survival in patients with hepatocellular carcinoma. Hepatology 40:1352–1360
Bruix J, Sherman M, Llovet JM et al (2001) Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J. Hepatol. 35:421–430
Kojiro M, Roskams T (2005) Early hepatocellular carcinoma and dysplastic nodules. Semin Liver Dis 25:133–142
Roncalli M, Roz E, Coggi G et al (1999)The vascular profile of regenerative and dysplastic nodules of the cirrhotic liver: implications for diagnosis and classification. Hepatology 30: 1174–1178
Borzio M, Fargion S, Borzio F et al (2003) Impact of large regenerative, low grade and high grade dysplastic nodules in hepatocellular carcinoma development. J Hepatol 39:208–214
Terjung B, Lemnitzer I, Dumoulin FL et al (2003) Bleeding complications after percutaneous liver biopsy. An analysis of risk factors. Digestion 67:138–145
Torzilli G, Minagawa M, Takayama T et al (1999) Accurate preoperative evaluation of liver mass lesions without fine-needle biopsy. Hepatology 30:889–893
Zoli M, Magalotti D, Bianchi G et al (1996) Efficacy of a surveillance program for early detection of hepatocellular carcinoma. Cancer 78:977–985
Oka H, Yamamoto S, Kuroki T et al (1990) Prospective study of early detection of hepatocellular carcinoma in patients with cirrhosis. Hepatology 12:680–687
Bennett GL, Krinsky GA, Abitbol RJ et al (2002) Sonographic detection of hepatocellular carcinoma and dysplastic nodules in cirrhosis: correlation of pretransplantation sonography and liver explant pathology in 200 patients. AJR Am J Roentgenol 179:75–80
Shapiro RS, Wagreich J, Parsons RB et al (1998) Tissue harmonic imaging sonography: evaluation of image quality compared with conventional sonography. AJR Am J Roentgenol. 171:1203–1206
Tanaka S, Oshikawa O, Sasaki T et al (2000) Evaluation of tissue harmonic imaging for the diagnosis of focal liver lesions. Ultrasound Med Biol 26:183–187
Sheu JC, Chen DS, Sung JL et al (1985) Hepatocellular carcinoma: US evolution in the early stage. Radiology 155:463–467
Kim KA, Lee WJ, Lim HK et al (2003) Small hepatocellular carcinoma: ultrasonographic findings and histopathologic correlation. Clin Imaging 27:340–345
Ogata R, Majima Y, Tateishi Y et al (2000) Bright loop appearance; a characteristic ultrasonography sign of early hepatocellular carcinoma. Oncol Rep 7:1293–1298
Bru C, Maroto A, Bruix J et al (1989) Diagnostic accuracy of fine-needle aspiration biopsy in patients with hepatocellular carcinoma. Dig Dis Sci 34:1765–1769
Lencioni R, Pinto F, Armillotta N, Bartolozzi C (1996) Assessment of tumor vascularity in hepatocellular carcinoma: comparison of power Doppler US and color Doppler US. Radiology 201:353–358
Koito K, Namieno T, Morita K (1998) Differential diagnosis of small hepatocellular carcinoma and adenomatous hyperplasia with power Doppler sonography. AJR Am J Roentgenol 170:157–161
Kumada T, Nakano S, Toyoda H et al (2004) Assessment of tumor hemodynamics in small hepatocellular carcinoma: comparison of Doppler ultrasonography, angiography-assisted computed tomography, and pathological findings. Liver Int 24:425–431
Gaiani S, Volpe L, Piscaglia F, Bolondi L (2001) Vascularity of liver tumours and recent advances in doppler ultrasound. J Hepatol 34:474–482
Kudo M, Tochio H, Zhou P (2004) Differentiation of hepatic tumors by color Doppler imaging: role of the maximum velocity and the pulsatility index of the intratumoral blood flow signal. Intervirology 47:154–161
Fracanzani AL, Burdick L, Borzio M et al (2001) Contrast-enhanced Doppler ultrasonography in the diagnosis of hepatocellular carcinoma and premalignant lesions in patients with cirrhosis. Hepatology 34:1109–1112
Valls C, Cos M, Figueras J et al (2004) Pretransplantation diagnosis and staging of hepatocellular carcinoma in patients with cirrhosis: value of dual-phase helical CT. AJR Am J Roentgenol 182:1011–1017
Yamashita Y, Mitsuzaki K, Yi T et al (1996) Small hepatocellular carcinoma in patients with chronic liver damage: prospective comparison of detection with dynamic MR imaging and helical CT of the whole liver. Radiology 200:79–84
Nicolau C, Catala V, Vilana R et al (2004) Evaluation of hepatocellular carcinoma using SonoVue, a second generation ultrasound contrast agent: correlation with cellular differentiation. Eur Radiol 14:1092–1099
Quaia E, Calliada F, Bertolotto M et al (2004) Characterization of focal liver lesions with contrast-specific US modes and a sulfur hexafluoride-filled microbubble contrast agent: diagnostic performance and confidence. Radiology 232:420–430
Nicolau C, Vilana R, Catala V et al (2006) The importance of the evaluation of all vascular phases on contrast-enhanced sonography in the differentiation of benign from malignant focal liver lesions. AJR Am J Roentgenol 186(1):158–167
Vilana R, Llovet JM, Bianchi L et al (2003) Contrast-enhanced power Doppler sonography and helical computed tomography for assessment of vascularity of small hepatocellular carcinomas before and after percutaneous ablation. J Clin Ultrasound 31:119–128
Giorgio A, Ferraioli G, Tarantino L et al (2004) Contrast-enhanced sonographic appearance of hepatocellular carcinoma in patients with cirrhosis: comparison with contrast-enhanced helical CT appearance. AJR Am J Roentgenol 183:1319–1326
Gaiani S, Celli N, Piscaglia F et al (2004) Usefulness of contrast-enhanced perfusional sonography in the assessment of hepatocellular carcinoma hypervascular at spiral computed tomography. J Hepatol 41:421–426
Choi BI, Kim TK, Han JK et al (2000) Vascularity of hepatocellular carcinoma: assessment with contrast-enhanced second-harmonic versus conventional power Doppler US. Radiology 214:381–386
Bolondi L, Gaiani S, Celli N et al (2005) Characterization of small nodules in cirrhosis by assessment of vascularity: the problem of hypovascular hepatocellular carcinoma. Hepatology 42:27–34
Matsui O (2004) Imaging of multistep human hepatocarcinogenesis by CT during intra-arterial contrast injection. Intervirology 47:271–276
Takayasu K, Muramatsu Y, Furukawa H et al (1995) Early hepatocellular carcinoma: appearance at CT during arterial portography and CT arteriography with pathologic correlation. Radiology 194:101–105
Kim T, Federle MP, Baron RL et al (2001) Discrimination of small hepatic hemangiomas from hypervascular malignant tumors smaller than 3 cm with three-phase helical CT. Radiology 219:699–706
Hayashi PH, Trotter JF, Forman L et al (2004) Impact of pretransplant diagnosis of hepatocellular carcinoma on cadveric liver allocation in the era of MELD. Liver Transpl 10:42–48
Albrecht T, Blomley M, Bolondi L et al (2004) Guidelines for the use of contrast agents in ultrasound. January 2004. Ultraschall Med 25:249–256
Marrero JA, Hussain HK, Nghiem HV et al (2005) Improving the prediction of hepatocellular carcinoma in cirrhotic patients with an arterially-enhancing liver mass. Liver Transpl 11:281–289
Dietrich CF, Ignee A, Trojan J et al (2004) Improved characterisation of histologically proven liver tumours by contrast-enhanced ultrasonography during the portal-venous and specific late phase of SHU 508A. Gut 53:401–405
von Herbay A, Vogt C, Willers R, Haussinger D (2004) Real-time imaging with the sonographic contrast agent SonoVue: differentiation between benign and malignant hepatic lesions. J Ultrasound Med 23:1557–1568
Vilana R, Bru C, Bruix J et al (1993) Fine-needle aspiration biopsy of portal vein thrombus: value in detecting malignant thrombosis. AJR Am J Roentgenol 160:1285–1287
Dodd GD III, Memel DS, Baron RL et al (1995) Portal vein thrombosis in patients with cirrhosis: does sonographic detection of intrathrombus flow allow differentiation of benign and malignant thrombus? AJR Am J Roentgenol 165:573–577
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Nicolau, C., Bru, C. (2006). Characterisation of Hepatocellular Carcinoma in Cirrhosis. In: Lencioni, R. (eds) Enhancing the Role of Ultrasound with Contrast Agents. Springer, Milano. https://doi.org/10.1007/88-470-0476-4_3
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DOI: https://doi.org/10.1007/88-470-0476-4_3
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